The Gray BRCA Pre-Cancer Atlas seeks to transform treatment and prevention for BRCA1/2 mutation-associated cancers through innovative research and new profiling methods.
ADVANCING CANCER RESEARCH
The Gray Foundation is transforming how we identify and study the earliest stages of cancer to enable treatment before the cancer spreads. The Atlas focuses on breast and ovarian cancers and the impact on these diseases of mutations in BRCA1 or BRCA2 genes, which substantially increases the hereditary risk of cancer and also impacts treatment options for spontaneous cancers.
Meet the People Behind the Atlas
Publications & Projects
A human breast atlas integrating single-cell proteomics and transcriptomics.
Publication
Video Overview
An atlas of substrate specificities for the human serine/threonine kinome.
Publication
Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of BRCA2 mutation carriers.
Publication
Data
Ovarian Cancer with Annotation - LSP15343
Ovarian Cancer with Annotation - LSP15327
Single-Cell human breast atlas integrating single-cell proteomics and transcriptomics
Single-Cell RNA Sequencing of Breast Tissues
BRCA1-associated-9
BRCA1-associated-8
BRCA WT vs BRCA1 associated TNBC